To administer bretylium to a patient weighing 170 lbs. you convert their weight to kilograms, calculate the dosage in micrograms per minute, and then multiply by 60 to get an hourly dose. Given the concentration of 1 mg/mL, you would administer approximately 23.133 mL of the medication per hour.
To calculate the amount of bretylium to administer per hour to a patient with ventricular fibrillation, we need to first convert the patient's weight from pounds to kilograms since the dosage is based on weight in kilograms.
Given that 1 pound is approximately equivalent to 0.453592 kilograms, we have:
170 lbs * 0.453592 kg/lb = 77.11 kg (rounded to two decimal places)
The prescribed dosage is 5 mcg/kg/minute, therefore:
5 mcg/kg/minute * 77.11 kg = 385.55 mcg/minute
Since there are 60 minutes in an hour, we convert the dosage to an hourly basis:
385.55 mcg/minute * 60 minutes/hour = 23133 mcg/hour or 23.133 mg/hour
The medication comes mixed as 50 mg in 50 mL, meaning there is 1 mg/mL. To find out how many mL to administer per hour, we use the hourly dosage in mg and divide by the concentration:
23.133 mg/hour ÷ 1 mg/mL = 23.133 mL/hour
Therefore, the patient should be administered approximately 23.133 mL of the medication per hour.
The complete question is here:
A patient with ventricular fibrillation is prescribed with bretylium 5 mcg/kg/minute. the medication comes mixed 50 mg in 50 ml of 0.9 % normal saline. the patient's weight is 170 lbs. how much of the medication will you administer per hour?