Answer: increased myocardial oxygen use
Explanation:Increased myocardial oxygen use is a potential adverse response to bronchodilator therapy, especially with beta-agonists. Beta-agonists can stimulate beta receptors in the heart, leading to increased heart rate (tachycardia) and increased contractility of the heart muscle. These effects can result in an increased demand for oxygen by the heart (increased myocardial oxygen use). In individuals with underlying cardiovascular conditions, this increased demand for oxygen can be problematic and potentially lead to angina (chest pain) or cardiac arrhythmias.