Answer & Explanation:
The quotation that is a stage direction is:
"LADY MACBETH begins to rub her hands together."
A stage direction is a part of a play that tells the actors what they should do on stage. In this case, the stage direction is telling the actor playing Lady Macbeth to start rubbing her hands together. This is an important detail to include in the play because it helps to convey Lady Macbeth's mental state and inner turmoil. The rubbing of her hands is a physical manifestation of her guilt and anxiety,