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Which of Koch's postulates can not be applied to bacterial vaginosis caused by Gardnerella vaginalis?

The same pathogen must be present in every case of the disease
The pathogen must be ioslated from the diseased host and grown in pure culture
The pathogen from pure culture must cause the disease when it's inoculated into a healthy, susceptible host
The pathogen must be isolated from the inoculated host and must be shown to be the original organism

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Answer: The same pathogen must be present in every case of the disease.

Explanation: Koch's postulates are a set of criteria used to establish a causal relationship between a specific microorganism and a disease. However, when it comes to bacterial vaginosis caused by Gardnerella vaginalis, the first postulate may not be applicable. Bacterial vaginosis is a condition that can involve multiple microorganisms, and it is not solely caused by Gardnerella vaginalis alone. Therefore, the presence of Gardnerella vaginalis in every case of the disease may not hold true, making it difficult to apply the first postulate in this case.

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