Question

Which of the following reagents can be used to convert 1-pentyne into a ketone? O 1.9-BBN 2. NaOH, H2O2 1.BH3-THF 2. NaOH, H202 O H2SO4, H20, HgSO4 1. Disiamylborane 2. NaOH, H202

Answer 1

The reagent that can be used to convert 1-pentyne into a ketone is 2. NaOH, H2O2.

Step-by-step explanation:

The reagent that can be used to convert 1-pentyne into a ketone is 2. NaOH, H2O2.

In this reaction, sodium hydroxide (NaOH) and hydrogen peroxide (H2O2) are used as oxidizing agents to convert the alkyne (1-pentyne) into a ketone.

Answer 2

The reagent combination that can be used to convert 1-pentyne into a ketone is
`\(H_2SO_4, H_2O, HgSO_4\)`. Option 4.

The conversion of 1-pentyne into a ketone involves multiple steps. Let's evaluate the provided reagents:

1.
`\(1.9\text{-BBN}\)` - This is a boron-based reducing agent and is not typically used to convert alkynes into ketones. It is more commonly employed for reduction reactions.

2.
`\(NaOH, H_2O_2\)` - This is a reagent combination that can be used for oxidative cleavage of alkynes. In the case of 1-pentyne, it would result in the formation of carboxylic acids, not a ketone.

3.
`\(BH_3\text{-THF}, NaOH, H_2O_2\)` - This combination involves hydroboration-oxidation. It is known to convert alkynes into aldehydes, not ketones.

4.
`\(H_2SO_4, H_2O, HgSO_4\)` - This combination is commonly used for the hydration of alkynes, resulting in the formation of ketones.

5.
`\(Disiamylborane, NaOH, H_2O_2\)` - Similar to option 3, this combination involves hydroboration-oxidation, leading to the formation of aldehydes, not ketones.

Therefore, the reagent combination that can be used to convert 1-pentyne into a ketone is
`\(H_2SO_4, H_2O, HgSO_4\)` (option 4).