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Put the steps of B-cell activation in the correct order from first to last. Items in orde Items (6 items) (Drag and drop into the appropriate area) Each B cell rearranges its DNA to create a unique B-cell receptor B cells become activated by interacting with helper T cells. B cells undergo clonal selection Antibodies released by plasma cells bind to antigen so they will be destroyed by other immune system cells. B cells digest antigens that are bound to the antibodies on their surface Bcells display antigens in MHC dass Il receptors on the cell surface

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Final answer:

The steps of B-cell activation include rearranging DNA to create a unique B-cell receptor, interacting with helper T cells, undergoing clonal selection, the release of antibodies by plasma cells, digesting antigens, and displaying antigens on the cell surface.

Step-by-step explanation:

Steps of B-cell Activation

  1. Each B cell rearranges its DNA to create a unique B-cell receptor.
  2. B cells become activated by interacting with helper T cells.
  3. B cells undergo clonal selection.
  4. Antibodies released by plasma cells bind to antigen so they will be destroyed by other immune system cells.
  5. B cells digest antigens that are bound to the antibodies on their surface.
  6. B cells display antigens in MHC class II receptors on the cell surface.

User Simon Schnell
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This is the correct order of the steps of B-cell activation from first to last:

  1. Each B cell rearranges its DNA to create a unique B-cell receptor.
  2. B cells become activated by interacting with helper T cells.
  3. B cells display antigens in MHC class II receptors on the cell surface.
  4. B cells undergo clonal selection.
  5. B cells digest antigens that are bound to the antibodies on their surface.
  6. Antibodies released by plasma cells bind to antigen so they will be destroyed by other immune system cells.

What are these steps?

Each B cell rearranges its DNA to create a unique B-cell receptor. This process is called somatic hypermutation and it allows each B cell to recognize a different antigen.

B cells become activated by interacting with helper T cells. Helper T cells are activated by antigen-presenting cells (APCs) that have engulfed and digested the antigen. Once activated, helper T cells secrete cytokines that activate B cells.

B cells display antigens in MHC class II receptors on the cell surface. MHC class II receptors are molecules that present antigens to helper T cells. Activated B cells engulf and digest the antigen and then present the antigen fragments to helper T cells in their MHC class II receptors.

B cells undergo clonal selection. Clonal selection is the process by which B cells that recognize the antigen are selected to proliferate and differentiate into plasma cells.

B cells digest antigens that are bound to the antibodies on their surface. This process is called phagocytosis and it allows B cells to degrade the antigen and present it to helper T cells.

Antibodies released by plasma cells bind to antigen so they will be destroyed by other immune system cells. Plasma cells are differentiated B cells that produce and secrete antibodies. Antibodies are proteins that bind to specific antigens and mark them for destruction by other immune system cells, such as phagocytes.

User Stevanicus
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