Question

2 pts o Question 25 Which of the following factors are necessary for the initial contact activation of the intrinsic pathway? O II, III, IV, VII O X. I. II. V O XII, XI, HMWK, PK 1. XIII, HMWK, PK O X

Answer 1

The correct answer is XII, XI, HMWK, PK.

For the initial contact activation of the intrinsic pathway of blood coagulation, the factors involved are:

XII (Factor XII): Also known as the Hageman factor, it initiates the intrinsic pathway.

XI (Factor XI): It is activated by Factor XII and plays a role in the further activation of the pathway.

HMWK (High-Molecular-Weight Kininogen): It is a cofactor that helps in the activation of Factor XII.

PK (Prekallikrein): It is another cofactor that assists in the activation of Factor XII.

Therefore, the correct option is XII, XI, HMWK, and PK.