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How many ATP equivalents are made from the complete aerobic catabolism of isocitrate? A.9 ATP B. 10ATP C.11 ATP D. 12 ATP

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Isocitrate dehydrogenase catalyzes the rate-limiting reaction in the TCA cycle. Oxidation of 1 pyruvate molecule through the TCA cycle can yield 15 ATP equivalents. Although oxaloacetate and acetyl-CoA are impermeable to mitochondrial membranes, citrate and other intermediates of the cycle are permeable.

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