To solve the system by substitution, we can solve one of the equations for one of the variables, and then substitute that expression into the other equation.
From the second equation, we can solve for x:
x - 5y = 18
x = 5y + 18
Now we can substitute this expression for x into the first equation:
-3x + 5y = -4
-3(5y + 18) + 5y = -4
-15y - 54 + 5y = -4
-10y = 50
y = -5
Now that we know y = -5, we can substitute this value back into the expression we found for x:
x = 5y + 18
x = 5(-5) + 18
x = -7
Therefore, the solution to the system of equations is x = -7 and y = -5.