Answer: D
Explanation: The cities of the middle colonies in the 18th century experienced growth and exhibited all of the mentioned characteristics:
A. They grew larger than those in other regions: The middle colonies, which included cities like Philadelphia and New York, experienced significant population growth. These cities became major urban centers and were among the largest and most populous in the American colonies.
B. They grew because of active trade patterns: The middle colonies were known for their vibrant trade networks and commercial activity. The cities thrived due to their strategic locations, bustling ports, and involvement in international trade. Trade contributed to the economic growth and prosperity of these cities.
C. They were often dirty, crowded places: Like many cities during that time period, the cities in the middle colonies could be crowded, lacking proper sanitation, and suffering from issues of cleanliness and overcrowding. Urbanization and rapid population growth often led to challenges in maintaining infrastructure and public health.
Therefore, all of the provided statements accurately describe the cities of the middle colonies in the 18th century.