The location of regulatory sequences is related to their function because they are located in specific regions of DNA and control the expression of genes by binding to transcription factors. The location of these sequences determines which genes they regulate and how they are regulated. For example, promoter sequences are located upstream of the gene and are responsible for initiating transcription, while enhancer sequences can be located far away from the gene and are responsible for increasing the rate of transcription. The location of these sequences is critical for proper gene expression and can be influenced by various factors such as epigenetic modifications and changes in the cellular environment.