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T/F: secretin, a hormone produced by cells lining the duodenum, stimulates the pancreas to release bicarbonate ions.

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Answer:Secretin stimulates the secretion of a bicarbonate-rich pancreatic fluid (45). Secretin enters the blood stream or intestinal lumen and stimulates bicarbonate secretion (by interacting with pancreatic ductal cells), which neutralizes the pH of the gastric chyme upon entering the small intestine (83,84).

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