Lisinopril, an ACE inhibitor medication, is prescribed for the management of hypertension to prevent kidney disease progression. The most likely effect of lisinopril use is a reduction in blood pressure. ACE inhibitors work by blocking the production of a hormone called angiotensin II, which causes blood vessels to narrow and increases blood pressure. By blocking the production of angiotensin II, lisinopril allows blood vessels to relax and widen, which leads to a decrease in blood pressure. Additionally, lisinopril may also improve kidney function by decreasing the amount of protein in the urine, which is a sign of kidney damage. Therefore, the most likely effect of lisinopril use is a reduction in blood pressure and improved kidney function.