To begin, you may want to research Mayan art and murals to get a sense of the style and motifs used by the ancient civilization. You can then incorporate these elements into your own work, such as by using bold colors, intricate patterns, and hieroglyphics or other symbols.
You might also want to consider the subject matter of your mural. As Mayan murals often depicted scenes from everyday life or spiritual beliefs, you could choose a moment from your own life that is personally meaningful or significant to you. Alternatively, you could explore your own spiritual beliefs or cultural heritage and incorporate these themes into your work.
Finally, you could experiment with different painting techniques and styles to create a unique and visually striking mural. For example, you could use a stippling or pointillism technique to create intricate patterns or use bold, contrasting colors to create a sense of depth and dimension.