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given that rotenone and antimycin a are equally effective in blocking their respective sites in the electron transport chain, which would be a more potent poison? why?
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21 votes
given that rotenone and antimycin a are equally effective in blocking their respective sites in the electron transport chain, which would be a more potent poison? why?

User Cbalawat
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13 votes
13 votes

Answer: antimycin A is more potent than rotenone.Rotenone only inhibits electrons flow into the election transport chain at Complex 1 (electrons from NADH are restricted) Complex II (electrons for fatty acyl-CoA and FADH2) does not get affected by rotenone and so even though ETC becomes slow it does not stop completely.

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User Maku
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