Yes, the results of a microarray analysis of nerve cells and bone cells from the same person are likely to differ.
A microarray is a tool used to analyze the expression levels of thousands of genes simultaneously. It works by comparing the levels of mRNA transcripts in the samples to a reference sample, and determining which genes are up- or down-regulated in the test samples.
Nerve cells and bone cells are two different types of cells that have distinct functions and molecular profiles. They express different sets of genes and have different levels of gene expression. Therefore, when run through the same type of microarray, the mRNA profiles of nerve cells and bone cells are likely to differ significantly.
For example, nerve cells are specialized for transmitting electrical and chemical signals throughout the body, and express genes that support these functions, such as genes encoding ion channels and neurotransmitters. On the other hand, bone cells are specialized for maintaining the structure and strength of bones, and express genes that support these functions, such as genes encoding extracellular matrix proteins and bone remodeling enzymes.
Therefore, even though the samples are from the same person, the mRNA profiles of nerve cells and bone cells are likely to be different due to their distinct functions and gene expression profiles.