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How are the functions of the smooth and rough ER differentiated?

User Claus
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Step-by-step explanation:

The rough ER, studded with millions of membrane bound ribosomes, is involved with the production, folding, quality control and despatch of some proteins. Smooth ER is largely associated with lipid (fat) manufacture and metabolism and steroid production hormone production. It also has a detoxification function.

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User Juan Acevedo
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