Question

Why does a frameshift mutation usually cause more defects during protein

synthesis than a point mutation?
A. Frameshift mutations affect the whole chromosome.
B. Frameshift mutations only occur during translation.
C. Frameshift mutations can affect many amino acids.
D. Frameshift mutations are silent mutations.

Answer 1

Answer: C

Explanation: Because an insertion or deletion results in a frame-shift that changes the reading of subsequent codons and, therefore, alters the entire amino acid sequence that follows the mutation, insertions and deletions are usually more harmful than a substitution in which only a single amino acid is altered.