The volume of a rectangular prism is given by the formula V = lwh, where l, w, and h are the length, width, and height of the prism, respectively.
In this case, the width is x^2 inches, the length is xy^2 inches, and the height is xy inches.
Substituting these values into the formula, we get:
V = (xy^2)(x^2)(xy)
Simplifying, we get:
V = x^4y^3
Therefore, the expression that represents the volume of the rectangular prism in cubic inches is x^4y^3.