Graft rejection consists of sensitization, when T cells are stimulated, and effector when they attack the graft. The correct answer is A.
Graft rejection is an immune response that occurs when a transplanted organ or tissue is recognized as foreign by the recipient's immune system and attacked.
The process of graft rejection involves two main stages: sensitization and effector.
During sensitization, the recipient's immune system is exposed to the antigens present on the surface of the transplanted graft.
This exposure triggers an immune response, leading to the activation and proliferation of T cells.
These T cells then migrate to the site of the graft and begin to attack it, leading to tissue damage and destruction.
The effector phase of graft rejection is characterized by the infiltration of T cells, macrophages, and other immune cells into the graft tissue, resulting in further tissue destruction and ultimately graft failure.
Effector T cells are activated by antigen-presenting cells (APCs) that present antigens derived from the transplanted graft.
In summary, graft rejection is a complex immune response that involves the activation and proliferation of T cells, leading to tissue damage and destruction.
Efforts to prevent graft rejection have led to the development of immunosuppressive drugs and other treatments that target the immune system's response to the transplanted tissue. Therefore, the right answer is A.
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