Answer & Explanation: The Tenth Amendment best addresses the fears of the Anti-Federalists of a central government. It states that all powers not delegated to the federal government, nor prohibited by it to the states, are reserved to the states or to the people. This amendment reinforces the idea of federalism and limits the power of the federal government by reserving certain powers to the states. The Anti-Federalists were concerned that a strong central government would trample on the rights of the states and individuals, and the Tenth Amendment was added to the Bill of Rights to help alleviate those concerns.