HIV (Human Immunodeficiency Virus) is a virus that primarily targets the immune system's CD4+ T cells, also known as helper T-cells. These cells play a crucial role in the body's immune response by recognizing and responding to pathogens such as viruses, bacteria, and fungi. HIV attacks and destroys these cells, which can lead to severe damage to the immune system, making it harder for the body to fight infections and diseases.
If left untreated, HIV can significantly affect a person's immune response in several ways. Firstly, HIV can reduce the number of CD4+ T cells in the body, leading to a weakened immune system. As the virus replicates and destroys more CD4+ T cells, the body becomes increasingly vulnerable to opportunistic infections and cancers.
Secondly, HIV can impair the function of CD4+ T cells that remain in the body. Even if there are enough CD4+ T cells present in the body, they may not function correctly due to HIV's impact on their signaling pathways. This can lead to a weakened immune response and an increased risk of infections.