Based on the given pattern:
2 x 4 + 1 = 3 x 3
3 x 5 + 1 = 4 x 4
4 x 6 + 1 = __ + __
__ x 7 + 1 = __ x __
__ x __ + __ = __ + __
The general pattern is that the first term is multiplied by one more than itself, and then 1 is added to the result, which is equal to the second term squared.
When the first term is 25, the equation would look like:
25 x 26 + 1 = __ + __
The first blank would be filled with 26, and the second blank would be filled with 676 (which is 26 squared). So the complete equation would be:
25 x 26 + 1 = 26 + 676