Final answer:
Joe's symptoms could be indicative of a problem in his digestive system, specifically in either the small or large intestine.
Step-by-step explanation:
Joe's symptoms of fatigue, confusion, and negative emotions could be indicative of a problem in his digestive system. These symptoms could be caused by an issue in either the small intestine or the large intestine. Some possible conditions that could cause these symptoms include duodenal ulcers, maldigestion, malabsorption, hemorrhoids, diverticular disease, and constipation.
Joe really must talk with a medical services proficient who can survey his side effects, clinical history, and lead any important tests to give a more exact conclusion. This will assist with deciding the fundamental reason and guide fitting treatment or mediations.