To solve this expression, we use the order of operations, which is a set of rules that dictate the order in which we perform arithmetic operations. The order of operations is:
Parentheses
Exponents
Multiplication and Division (performed left to right)
Addition and Subtraction (performed left to right)
Using the order of operations, we can rewrite the expression as:
12 + (18 x 4) x 6 - 3
First, we perform the multiplication inside the parentheses:
12 + 72 x 6 - 3
Next, we perform the multiplication from left to right:
12 + 432 - 3
Then, we perform the addition and subtraction from left to right:
441
Therefore, 12 + 18 x 4 x 6 - 3 = 441.