Answer: The correct answer is: 2 left, 4 up, 1 back.
Step-by-step explanation: The location of the point (-2, 4, -1) in relation to the origin is best described as 2 units to the left, 4 units up, and 1 unit down. This is because each coordinate represents a direction and a distance from the origin, which is the point (0,0,0) in 3-dimensional space. The first coordinate (-2) represents the distance and direction in the x-axis, the second coordinate (4) represents the distance and direction in the y-axis, and the third coordinate (-1) represents the distance and direction in the z-axis. Therefore, we can conclude that the point is located 2 units to the left of the origin in the x-axis, 4 units up from the origin in the y-axis, and 1 unit down from the origin in the z-axis.