Final answer:
The correct condition for using the difference of squares method to factorize a polynomial is that the polynomial has two terms with opposite signs.
Step-by-step explanation:
The condition for using the difference of squares method to factorize a polynomial is that the polynomial must have two terms with opposite signs. Specifically, the polynomial should be in the form of a^2 - b^2 where a and b are any expressions. Using the difference of squares rule, such a polynomial can be factorized into (a + b)(a - b). This applies because when two positive numbers multiply, or two negative numbers multiply, the result is positive; however, when numbers with opposite signs are multiplied, the result is negative, which aligns with the characteristics of a difference of squares situation.