Answer:
-2 cases per month.
Explanation:
To find average rate of change, we find the slope of the endpoints.
Slope=

It "rose" by 16-22, or -6. It "ran" by 4-1 or 3. Therefore, we can use the slope equation to get:
, which is equivalent to -2.
Therefore, the average rate of change is a loss of 2 cases per month.