Answer:
A substitution mutation is a type of genetic mutation where one base pair in the DNA sequence is replaced with a different base pair. This can result in a change in the amino acid sequence of the protein that is translated from the DNA sequence. If the substitution mutation occurs in a non-coding region of the DNA, it may not have any effect on the organism.
On the other hand, a frameshift mutation is a type of genetic mutation where one or more base pairs are inserted or deleted from the DNA sequence. This can shift the reading frame of the DNA sequence, changing the way that the sequence is translated into amino acids. This can result in a completely different protein being produced, or a protein that is missing critical parts or has extra parts that don't function properly.
In general, frameshift mutations are likely to be more dangerous to an organism than substitution mutations. This is because frameshift mutations can result in a completely different protein being produced, or a protein that is missing critical parts or has extra parts that don't function properly. This can have a significant impact on the function of the protein, which can in turn impact the health and survival of the organism. Substitution mutations, on the other hand, may result in a change to a single amino acid in the protein, which may or may not have a significant impact on its function.
However, it is important to note that the impact of a mutation on an organism depends on a variety of factors, including the location of the mutation, the function of the protein that is affected, and the specific genetic and environmental context in which the organism exists. Therefore, it is not always the case that frameshift mutations are more dangerous than substitution mutations, and the impact of a particular mutation must be evaluated on a case-by-case basis.