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The rate of a reaction catalyzed by an enzymes usually ________ with temperature; however, at temperatures above the optimum range ________.

a. decreases; the reaction proceeds without the enzyme
b. increases; protein denaturation occurs
c. increases; the direction of the reaction reverses
d. increases; the reaction proceeds without the enzyme
e. decreases; prosthetic groups are necessary

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The answer to this question is B because the protein undergoes heat and undergoes denaturation.
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