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Teratogenic studies of insulin glarginewere undertaken in rats at doses up to0.36 mg/kg/day. This is equivalent towhich of the following?

(a) 360 cg/lb/day
(b) 792 mcg/lb/day
(c) 360 mg/lb/day
(d) 163.6 mcg/lb/day​

1 Answer

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Final answer:

The equivalent dosage of insulin glargine in mcg/lb/day is 163.6. The correct answer is option (d).

Step-by-step explanation:

The question is asking to determine the equivalent dosage of insulin glargine in mg/kg/day to other units of measurement. The given options are cg/lb/day, mcg/lb/day, and mg/lb/day.

To find the equivalent dosage, we can convert the given dose of 0.36 mg/kg/day to the desired unit.

To convert mg/kg/day to cg/lb/day, we can use the following conversion factors:
1 mg = 10 cg
1 kg = 2.205 lb

So, the equivalent dosage in cg/lb/day is 0.36 mg/kg/day * 10 cg/mg * (1/2.205) lb/kg = 1.635 cg/lb/day.

To convert mg/kg/day to mcg/lb/day, we can use the following conversion factors:
1 mg = 1000 mcg

So, the equivalent dosage in mcg/lb/day is 0.36 mg/kg/day * 1000 mcg/mg * (1/2.205) lb/kg = 163.636 mcg/lb/day.

Therefore, the correct answer is (d) 163.6 mcg/lb/day.

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