Final answer:
The non-compliant aspect with GLP requirements is having cats and mice used in the same room, which does not align with GLP standards for proper separation and contamination prevention.
Step-by-step explanation:
GLP Requirements for Animal Testing Facilities
The statement that is not compliant with Good Laboratory Practice (GLP) requirements regarding facilities used for animal testing is that 'Cats and mice should be used in the same room and separately from horses and pigs'. This is not compliant because GLP guidelines emphasize the need for proper separation of species to avoid contamination and distress among animals. GLP standards stipulate that facilities should be of suitable size and construction for the proper conduct of studies, mixing of animals used in different studies should be avoided, and there should be specific conditions for proper test article storage to ensure the integrity of the research and the wellbeing of animals.
Animal research is subject to ethical review and oversight by the Institutional Animal Care and Use Committee (IACUC), which ensures that animal research is conducted in accordance with ethical and regulatory standards. Facilities receiving federal funding must adhere to NIH guidelines, which are grounded in the principles of the three R's: replace, refine, and reduce. The goal of these guidelines is to minimize animal use and suffering and to ensure that alternatives to animal testing are considered wherever possible.