Question

Which of the following statements about dehydro cpiandrosterone (DHEA) is correct?

A. DHEA is a precursor to both male and female sex hormones.
B. DHEA levels typically decrease with age.
C. DHEA supplementation is universally recommended for all age groups.

Answer 1

Dehydroepiandrosterone (DHEA) is a prohormone that serves as a precursor to both male and female sex hormones, and its levels typically decrease with age. DHEA supplementation is not universally recommended for all age groups due to potential side effects and regulation issues.

Step-by-step explanation:

DHEA and Androgens

Dehydroepiandrosterone (DHEA) is an androgen produced in the zona reticularis. The following statements pertain to DHEA:

• A. DHEA is a precursor to both male and female sex hormones.: This is correct. DHEA acts as a prohormone and can be converted into more potent androgens like testosterone in males, and estrogens in females.
• B. DHEA levels typically decrease with age: This statement is also correct. As individuals age, particularly after 30, DHEA levels tend to decrease, potentially leading to various signs of aging and a condition in males known as andropause.
• C. DHEA supplementation is universally recommended for all age groups: This is not true. Supplementation recommendations are individualized and depend on various factors. DHEA and other prohormone supplements are controversial due to potential side effects, and their use is regulated in many countries.

Therefore, the correct statements about DHEA are that it is a precursor to both male and female sex hormones and that its levels typically decrease with age.