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Tau needs to be properly phosphorylated to maintain the structural integrity of the microtubule assembly.

a-true
b-false

User Jlmurph
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1 Answer

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Final answer:

The Tau protein needs to be properly phosphorylated to maintain the structural integrity of the microtubule assembly.

Step-by-step explanation:

True. The Tau protein needs to be properly phosphorylated in order to maintain the structural integrity of the microtubule assembly. Phosphorylation is a process in which a phosphate group is added to a protein, and in this case, when Tau becomes phosphorylated, it binds to and stabilizes microtubules.

However, when Tau becomes hyper-phosphorylated, its conformation changes, leading to the disassembly of microtubules and the formation of neurofibrillary tangles.

User Vardd
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