Final answer:
A change in pH from 7.40 to 7.25 indicates acidosis, since it falls below the normal blood pH range of 7.35 to 7.45.
Step-by-step explanation:
A change of pH from 7.40 to 7.25 is indicative of acidosis. The normal blood pH range is between 7.35 to 7.45. Any pH value below this range suggests a condition where there is an excess of hydrogen ions (H+), resulting in a lower pH and therefore, acidosis.
This condition affects the function of enzymes, which are vital for nearly all biochemical reactions in the body. Certain buffers, including the bicarbonate system in the human body, help to maintain the pH level within the normal range.