Final answer:
Lymphogranuloma venereum is a sexually transmitted disease caused by certain types of Chlamydia trachomatis, leading to large swollen lymph nodes known as buboes.
Step-by-step explanation:
Lymphogranuloma venereum is a sexually transmitted systemic disease caused by certain serovars of Chlamydia trachomatis. This condition is especially prevalent in tropical regions and has the potential to co-occur with HIV infection. After infection, the lymphatic system is compromised, leading to the formation of buboes, which are large swollen lymph nodes that can burst and release pus through the skin. In advanced cases, the male genitals can become significantly enlarged, and in women, the rectum may become narrowed.