Final answer:
Substance abusers, despite their personality differences, commonly experience drug withdrawal and the effects of addiction and dependency, which include physical and psychological dimensions and can lead to dangerous tolerance levels.
Step-by-step explanation:
Despite vast personality differences, virtually all substance abusers experience drug withdrawal when trying to discontinue the use of a substance. Drug addiction and dependence are critical aspects of substance use disorders that encompass both physical and psychological dimensions. The condition of drug withdrawal can be markedly unpleasant and, in the case of substances like alcohol and barbiturates, potentially life-threatening.
Physical dependence results in physiological withdrawal symptoms, whereas psychological dependence includes an emotional need for the drug, often to relieve psychological distress. Additionally, those with substance use disorders might develop tolerance, necessitating increasing amounts of the drug to achieve the same effects - which could lead to dangerous levels of consumption. This combination of tolerance and withdrawal signifies a deepening cycle of addiction, often requiring professional intervention and rehabilitation for recovery.