Question

There are two types of in vivo skin tests used to detect specifically sensitized T lymphocytes. The first is the intradermal test, in which antigen is injected into the skin. The second is the patch test, in which the antigen is absorbed through the skin. What is the best-known intradermal test called?

Mantoux
Bence Jones
Lewis
Duffy
Kell

Answer 1

The best-known intradermal test used to detect specifically sensitized T lymphocytes is the Mantoux test, which is primarily used for diagnosing tuberculosis.

Step-by-step explanation:

The best-known intradermal test for detecting specifically sensitized T lymphocytes is known as the Mantoux test. This test is a classical method for delayed hypersensitivity, especially used to diagnose tuberculosis (TB). During the Mantoux test, bacterial proteins from Mycobacterium tuberculosis are injected into the skin.

A positive test result is indicated by a raised red area called an induration a couple of days later. This induration indicates the presence of an immune response due to activated macrophages, confirming that the patient has been exposed to TB and exhibits a cellular immune response to it.