Final answer:
Optimal sarcomere length for maximal tension is between 2.0 and 2.5 micrometers, where there is the greatest overlap between myosin and actin filaments.
Step-by-step explanation:
The optimal sarcomere length for maximum tension development in a single sarcomere is when the overlap between myosin and actin filaments is greatest. The overlapping is most favorable when the sarcomere length is between 2.0 and 2.5 micrometers. Within this range, the myosin heads and actin-binding sites have the maximal interaction, allowing for the most cross-bridge formation, and thereby, the generation of maximal tension during muscle contraction. If the sarcomere is shorter than this optimal range, the actin filaments may overlap and interfere with each other, whereas if it is stretched longer, there will be insufficient overlap, leading to fewer myosin-actin interactions and thus, reduced tension.