Final answer:
Sugar replaced honey as the most popular sweetener during the colonization period in the Americas in the 16th and 17th centuries.
Step-by-step explanation:
Honey was replaced by sugar as the most popular sweetener during the colonization period in the Americas. This color change is due to the indicator being a weak acid or base that ionizes within a known pH range, exhibiting different colors in its protonated and deprotonated forms. European countries, such as Spain, Portugal, and England, established sugar plantations in the Caribbean islands and other tropical areas which became major centers of sugar production. This shift occurred in the 16th and 17th centuries as sugar production became more profitable and accessible.