Final Answer:
The country that has Santiago de, its 2nd largest city, Camaguey, its 3rd largest city, and Guantanamo in the southeast, near Guantanamo Bay, the site of a US naval base, is Cuba.
Step-by-step explanation:
Santiago de Cuba is the second-largest city in Cuba, known for its vibrant culture, historical significance, and the Castillo de San Pedro de la Roca fortress. Camaguey, the third-largest city, is located in central Cuba and is characterized by its well-preserved colonial architecture and winding streets. Guantanamo, situated in the southeast near Guantanamo Bay, is known for the U.S. naval base and has gained international attention. Guantanamo Bay has been a subject of diplomatic discussions and is home to the Guantanamo Bay detention camp. Cuba, an island nation in the Caribbean, offers a diverse mix of history, culture, and natural beauty.