Final answer:
Charlotte is the largest city in North Carolina, nicknamed 'Queen City' and 'Hornet's Nest' due to its historical ties to British royalty and the American Revolution.
Step-by-step explanation:
The largest city in North Carolina, known by the nicknames Queen City or Hornet's Nest, is Charlotte. With a rich history dating back to colonial times, Charlotte was named in honor of the German princess Charlotte of Mecklenburg-Strelitz, the queen consort of King George III of Britain.
The nickname 'Hornet's Nest' was bestowed upon the city by British General Cornwallis during the American Revolutionary War, after he encountered fierce resistance from the city's residents.