Final answer:
Yes, you can run driver rollback in Safe Mode. Safe Mode starts with only essential system programs and services, allowing troubleshooting of drivers or hardware issues.
Step-by-step explanation:
The statement that you can run driver rollback at any time, even when the system starts in Safe Mode, is true. Safe Mode is a diagnostic mode of a computer operating system (OS). It can also refer to a mode of operation by application software. In Windows, Safe Mode only allows essential system programs and services to start up at boot. This limited access mode can help to troubleshoot software issues, such as drivers or hardware that cause stability problems. When you are in Safe Mode, you can revert to previous drivers through the Device Manager, which can be essential in situations where a new driver update causes system instability.