Final answer:
DNA replication in archaea is most similar to that of eukaryotes due to shared replication proteins and a closer evolutionary relationship reflected in common gene sequences and biochemical pathways.
Step-by-step explanation:
Based on replication proteins, DNA replication in archaea is most similar to that of eukaryotes. Unlike bacteria, archaea share several traits with eukaryotes such as the presence of certain proteins and metabolic pathways. For example, in eukaryotes the enzymes of replication, like DNA polymerase alpha, which is similar to prokaryotic DNA polymerase-I, and DNA polymerase delta, operate in a fashion analogous to certain archaeal replication systems. Additionally, the structure and function of these replication proteins point towards a closer evolutionary relationship between archaea and eukaryotes, rather than between archaea and bacteria. This connection is evident in the certain gene sequences and biochemical mechanisms that archaea and eukaryotes have in common but which are absent in bacteria. Thus, when considering the similarities in the DNA replicase systems or replisomes, it is the archaea's replication machinery that aligns more closely with that of eukaryotes.