Final answer:
It is true that overuse of tranquilizers can lead to both psychological and physiological dependence, with the body requiring more of the drug over time to achieve the same effects (tolerance), leading to higher risks of overdose and death.
Step-by-step explanation:
When tranquilizers are overused, psychological and physiological dependence occurs. The statement is true. Physiological dependence involves changes in the body's normal functions, leading to withdrawal symptoms if the drug use is stopped. Psychological dependence refers to the emotional need for the drug, often used to alleviate psychological distress. Tolerance, a concept linked to physiological dependence, describes the need for increasing amounts of a drug to achieve the effects that were previously attained with smaller doses. This can lead to dangerous levels of consumption and even the risk of overdose and death. Central nervous system depressants like alcohol can result in both physical and psychological dependence, which heightens their potential for abuse.