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The interactions that are typically involved in peripheral proteins binding to biological membranes?

A) Covalent bonds and disulfide linkages
B) Hydrogen bonding and van der Waals forces
C) Phosphodiester bonds and peptide bonds
D) Ionic bonds and hydrophobic interactions

User Desert Ice
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Final Answer:

The interactions that are typically involved in peripheral proteins binding to biological membranes are Ionic bonds and hydrophobic interactions, so the correct option is D) Ionic bonds and hydrophobic interactions

Step-by-step explanation:

Peripheral proteins binding to biological membranes typically involve a combination of ionic bonds and hydrophobic interactions.

Ionic bonds are formed between charged groups on the peripheral protein and the charged components of the membrane, such as phospholipid head groups. These electrostatic attractions contribute to the stability of the protein-membrane complex.

Meanwhile, hydrophobic interactions occur between nonpolar regions of the protein and the hydrophobic core of the lipid bilayer, helping anchor the protein to the membrane.

The presence of ionic bonds is crucial for specificity in binding, as different proteins may interact with membrane components that carry opposite charges.

This specificity ensures the proper functioning of various cellular processes. On the other hand, hydrophobic interactions contribute to the overall stability of the protein-membrane association by minimizing exposure to the aqueous environment.

This dual nature of binding forces allows peripheral proteins to maintain dynamic interactions with biological membranes, facilitating their roles in cellular signaling, transport, and structural support.

While covalent bonds and disulfide linkages are more characteristic of integral membrane proteins, peripheral proteins rely on weaker, reversible forces like ionic bonds and hydrophobic interactions to transiently associate with the membrane.

This flexibility enables peripheral proteins to dynamically respond to cellular signals and participate in diverse cellular functions without being permanently embedded in the lipid bilayer.

The interactions that are typically involved in peripheral proteins binding to biological membranes are Ionic bonds and hydrophobic interactions, so the correct option is D) Ionic bonds and hydrophobic interactions

User Saurabh Vardani
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