Question

A sentinel node is the first lymph node __________.

a. To produce an antibody in an immune reaction
b. That receives lymph drainage from a body area suspected of cancer
c. To filter pathogens in the lymphatic system
d. To develop into a secondary lymphoid organ

Answer 1

A sentinel node is the first lymph node to receive lymph from an area of the body suspected of cancer and serves as a primary screening point for metastatic cancer cells in the lymphatic system.

Step-by-step explanation:

Lymph nodes play a critical role in the immune system by filtering pathogens that have been gathered by lymph as it drain from body tissues. These nodes house populations of T and B lymphocytes, which are vital for adaptive immune responses, alongside other cells such as dendritic cells and macrophages. The sentinel node is identified in procedures where the spread of cancer is being evaluated. It serves as the primary screening point for metastatic cancer cells traveling through the lymphatic system. Since it is the first node to encounter lymph from affected tissues, examining the sentinel node can provide valuable diagnostic information for cancer staging and treatment planning.