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Which of the following cells would NOT be found in a germinal center in a lymph node?

a. Plasma cells
b. B lymphocytes
c. T lymphocytes
d. Monocytes

User Dracorat
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Final answer:

Monocytes are the cells that would NOT be found in germinal centers of a lymph node. Germinal centers consist of mature B cells, T cells that assist them, and plasma cells, while monocytes differentiate into other cell types outside of germinal centers.

Step-by-step explanation:

The cell that would NOT be found in a germinal center in a lymph node is d. Monocytes. Germinal centers are areas within lymph nodes where mature B cells proliferate, differentiate, and mutate their antibody genes through a process called somatic hypermutation following antigen activation. These centers are crucial for the adaptive immune system, which is responsible for generating a targeted immune response against specific pathogens.Plasma cells are differentiated B cells that secrete antibodies, critical components of the humoral immune response. B lymphocytes, or B cells, are responsible for producing antibodies and can differentiate into plasma cells. T lymphocytes, or T cells, are also present in germinal centers as they are involved in helping B cells to produce the most effective antibodies. In contrast, monocytes, which are precursors to macrophages and dendritic cells, are not a characteristic feature of germinal centers. Thus, among the cells listed, monocytes do not typically reside in germinal centers.

User Vikash Kumar Verma
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