Final answer:
The 7th Fleet's area of responsibility is the Western Pacific Ocean, and it operates in the Asia-Pacific region. West Africa was the region most directly involved in the Trans-Atlantic slave trade.
Step-by-step explanation:
The area of responsibility for the 7th Fleet is a) Western Pacific Ocean. The 7th Fleet is a part of the United States Navy and is responsible for operations in the Asia-Pacific region, including the Pacific Ocean around North America, South America, and extending towards the western edges of the Indian Ocean. The 7th Fleet's area of operation covers more than 124 million square kilometers, ranging from the International Date Line to the India/Pakistan border; and from the Kuril Islands in the North to the Antarctic in the South.
Regarding the Trans-Atlantic slave trade, the region of Africa most directly involved was b) West Africa. This area was the starting point for the majority of the slave trade that transported African people to the Americas.