Final answer:
Rectal administration is, contrary to the false statement, often appropriate for use in children. This route bypasses digestive enzymes, avoids upper GI irritation, and helps patients with swallowing difficulties.
Step-by-step explanation:
The statement that is NOT true regarding rectal administration is that it is 'not appropriate for use in children'. In fact, rectal administration is a route of administration that is often used in children who cannot take medications orally due to vomiting or other issues. This method of drug delivery is beneficial as it bypasses the action of digestive enzymes, avoids irritation to the upper GI tract, and is useful in patients with dysphasia who have difficulty swallowing. Rectal administration is, contrary to the false statement, often appropriate for use in children. This route bypasses digestive enzymes, avoids upper GI irritation, and helps patients with swallowing difficulties.